産業分類 ： 農業，林業
アピールポイント
● mRNAの配列特異的に蛍光標識するため生菌だけを検出。DNAとは反応しないのでゲノム由来のノイズはゼロ
● グラム陽性菌・陰性菌が混在している状態でもペプチドクリカンの厚みに関係なく同時検出可能
● 1細胞レベルで可視化され、共生関係など微生物の相互作用の解明や、難培養細菌の有用遺伝子探索に最適
アピールポイント
● mRNAの配列特異的に蛍光標識するため生菌だけを検出。DNAとは反応しないのでゲノム由来のノイズはゼロ
● グラム陽性菌・陰性菌が混在している状態でもペプチドクリカンの厚みに関係なく同時検出可能
● 1細胞レベルで可視化され、共生関係など微生物の相互作用の解明や、難培養細菌の有用遺伝子探索に最適
研究者のねらい
抗生物質やサプリメント剤など微生物の有用機能物質は私達の生活の中で様々に利用されていますが、これまでの微生物研究は単菌分離培養が可能な種のみが対象でした。しかし、環境中の99%以上の微生物は単菌分離培養が難しいことから、これらの微生物資源・遺伝子資源の利用方法として、近年では遺伝子配列を読む「メタゲノム解析」が身近なツールになりました。一方、得られる情報はバラバラにされた遺伝子配列です。そこで、「誰がどの遺伝子を持っているのか？」を可視化することにしました。さらにその遺伝子が機能しているかどうかを知るために、mRNAを標的分子に選びました。
Notice (8): Undefined variable: titleflg [APP/Template/Seeds/view.ctp, line 687]Code Context if($photoparts && !$titleflg){
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論文：1. H. Takahashi et al. Scientific Reports, 8, 7770. (2018) ; 2. H. Takahashi et al. Scientific Reports, 10, 9588. (2020).
プレスリリース：https://www.hiroshima-u.ac.jp/news/58447
研究室HP：http://www.okamuray.hiroshima-u.ac.jp/
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論文：1. H. Takahashi et al. Scientific Reports, 8, 7770. (2018) ; 2. H. Takahashi et al. Scientific Reports, 10, 9588. (2020).
プレスリリース：https://www.hiroshima-u.ac.jp/news/58447
研究室HP：http://www.okamuray.hiroshima-u.ac.jp/
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(int) 70 => '畜産学・獣医学',
(int) 71 => '境界農学',
(int) 72 => '薬学',
(int) 73 => '基礎医学',
(int) 74 => '境界医学',
(int) 75 => '社会医学',
(int) 76 => '内科系臨床医学',
(int) 77 => '外科系臨床医学',
(int) 78 => '歯学',
(int) 79 => '看護学'
]
$area = object(App\Model\Entity\Area) {
'id' => (int) 79,
'parent_id' => (int) 44,
'name' => '看護学',
'name_en' => 'Nursing ',
'keywords' => '基礎看護学,臨床看護学,生涯発達看護学,地域・老年看護学',
'keywords_en' => 'Fundamental nursing,Clinical nursing,Lifelong developmental nursing',
'description' => '看護学に関する情報です',
'description_en' => 'about Nursing informations',
'body' => '基礎看護学 臨床看護学 生涯発達看護学 地域・老年看護学 に関する情報です',
'body_en' => 'Nursing includes Fundamental nursing,Clinical nursing,Lifelong developmental nursing,Community health/ Gerontological nurisng informations. ',
'status' => true,
'created' => object(Cake\I18n\FrozenTime) {},
'modified' => object(Cake\I18n\FrozenTime) {},
'idkey' => 'd1fe173d08e959397adf34b1d77e88d7',
'[new]' => false,
'[accessible]' => [
'*' => true,
'id' => false
],
'[dirty]' => [],
'[original]' => [],
'[virtual]' => [],
'[hasErrors]' => false,
'[errors]' => [],
'[invalid]' => [],
'[repository]' => 'Areas'
}
$arealists = [
(int) 0 => ''
]
$categorylists = [
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]
$mainphotourl = '/resized_tmp/users/4008/profile.jpg'
$mainphotobase = '/var/www/vhosts/hutdb.hiroshima-u.ac.jp/httpdocs/resized_tmp/users/4008'
$notfound = (int) 0
$exists = (int) 1
$nameparts = ' 大学院統合生命科学研究科 岡村 好子 教授'
$nameparts_en = ' '
$category = ' '
$profileparts = '<img src="/resized_tmp/users/4008/profile.jpg" style="max-width:150px;" class="img-thumbnail" alt=""/>'
$categoryparts = '<span style="float:right;font-size:1.4em;">産業分類 ： 農業，林業</span>'
$categoryparts_blowser = '<p class="hidden-print">産業分類 ： 農業，林業</p>'
$profile = (int) 0
$idkey = 'https://seeds.office.hiroshima-u.ac.jp/profile/ja.d69a192d7da98025520e17560c007669'
$photourl = 'http://seeds.office.hiroshima-u.ac.jp/profile/image/portrait/https://seeds.office.hiroshima-u.ac.jp/profile/ja.d69a192d7da98025520e17560c007669.jpg'
$photourl2 = 'https://seeds.office.hiroshima-u.ac.jp/profile/image/portrait/https://seeds.office.hiroshima-u.ac.jp/profile/ja.d69a192d7da98025520e17560c007669.jpg'
$i = (int) 5
$photoparts = '<div class="pl20 pr20"><div class="row photos"></div><!-- row --></div>'
$cnt = (int) 0
$thename = 'p4'
$thenum = (int) 4
$filename = '4.jpg'
$tmp1 = '/var/www/vhosts/hutdb.hiroshima-u.ac.jp/httpdocs/files_tmp/seedtmps/1149/4.jpg'
$tmp2 = '/var/www/vhosts/hutdb.hiroshima-u.ac.jp/httpdocs/files/4.jpg'include - APP/Template/Seeds/view.ctp, line 687
Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1435
Cake\View\View::_render() - CORE/src/View/View.php, line 1393
Cake\View\View::render() - CORE/src/View/View.php, line 892
Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 791
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 256
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Middleware\CsrfProtectionMiddleware::__invoke() - CORE/src/Http/Middleware/CsrfProtectionMiddleware.php, line 133
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 170
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
研究内容
備考
特許：特願2017-085299「ＲＮＡ検出方法」
論文：1. H. Takahashi et al. Scientific Reports, 8, 7770. (2018) ; 2. H. Takahashi et al. Scientific Reports, 10, 9588. (2020).
プレスリリース：https://www.hiroshima-u.ac.jp/news/58447
研究室HP：http://www.okamuray.hiroshima-u.ac.jp/
